Tag: preclinical
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Fine-Tuning Process Devised for Gene Therapies
Researchers designed a technique to adjust the volume of proteins from gene therapy released into patients, providing more control for complex diseases.
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3-D Printed Scaffold Helps Regrow Soft Tissue
Researchers developed a biodegradable polymer for printed implant scaffolds that in lab rodents maintains its shape to encourage cell and tissue growth.
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Covid-19 Nasal Spray Vaccine Discontinued
A biotechnology company is discontinuing further work on a Covid-19 vaccine nasal spray after clinical trial results show it produces little immune response.
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Long-Acting Capsule Helps Reduce Opioid Use
A capsule designed to take once a week is shown in animal tests to continuously deliver a craving-reduction drug in that time and suppress opioid intake.
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Flexible Electrodes Devised for Implanted Devices
Biomedical engineers designed flexible electrodes that in lab tests safely connect and deliver electrical current to animal hearts and brains.
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Low Cost Vaccine, Patch Device Produce Immune Responses
Tests with lab mice show one dose of a lower cost Covid-19 vaccine given with a needle-free patch generates strong antibody and cellular immune responses.
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Electronic Device Cuts Bacterial Lab Test Time
An electronic device for assessing bacteria in blood samples is shown to meet conventional lab culture standards in a fraction of the usual testing time.
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Crispr Treatment Leads to Durable Cholesterol Reduction
A developer of gene editing for inherited heart disease reports lab monkeys given its therapy experience lower cholesterol levels for at least eight months.
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Small Biz Grant Funds Covid-19 Antiviral Therapy
A biotechnology company developing cancer therapies is receiving an NIH grant to extend its technology for antiviral peptides against the SARS-CoV-2 virus.
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Antibody Clears Covid-19 Variants, Enters Trial
A synthetic antibody is shown in lab tests to neutralize variants of the SARS-CoV-2 virus, and will be added to an ongoing clinical trial of Covid-19 therapies.