Tag: pharmaceuticals
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Leukemia Genetic Signature, Drug Candidates Identified
Researchers at University of Rochester in New York identified a set of genes behind the early growth of leukemia stem cells, and used those cells to highlight potential existing drugs with the chemistry to target those cells. The team led by senior investigator and Rochester medical school professor Craig Jordan — with colleagues from Weill…
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Researchers Designing New Drug for Chronic Pain
An interdisciplinary team from University of Liverpool and the Royal Liverpool University Hospital in the U.K. started research to design a new drug for the treatment of chronic pain. The £1.4 million ($US 2.22 million) grant for the project was awarded by the Medical Research Council, a supporter of medical research in the U.K., backed…
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Trial to Test Cardiac Potential of Anti-Inflammatory Drug
A clinical trial led by Brigham and Women’s Hospital in Boston will test the ability of a common anti-inflammatory drug to reduce rates of heart disease in high-risk patients. The trial is funded by grants from National Heart, Lung, and Blood Institute, part of National Institutes of Health. Over 2 million people in the United…
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European Businesses Expect 4 Percent Annual R&D Growth
A survey of executives from larger companies in Europe shows the executives anticipate spending four percent more per year on research and development in the years 2012 to 2014. The report is based on responses from 187 executives conducted in January through April 2012 in companies that spent €56 billion, which makes up about 40…
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New Methods Developed to Combat Drug Counterfeiting
Two presentations at the national meeting of the American Chemical Society in Philadelphia highlight new methods for combating counterfeit drugs, particularly in developing countries. Toni Barstis of Saint Mary’s College in Notre Dame, Indiana (pictured right) discussed a paper-strip test for Panadol, a pain killer based on acetaminophen, and Facundo Fernández at Georgia Tech in…
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FDA Approves Clinical Trial for H5N1 Vaccine
Infectious Disease Research Institute (IDRI) in Seattle and Medicago Inc. in Quebec City, Canada say the U.S. Food and Drug Administration approved their request to start a clinical trial of a vaccine for the H5N1 avian flu. The early stage — phase 1 — trial will test the safety and ability to generate an immune…
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Biopharm Raises $80 Million in Series C Venture Funds
Relypsa Inc., a clinical stage biopharmaceutical company in Santa Clara, California raised $80 million in series C venture funds, the third round of financing after initial start-up. New investor Sibling Capital LLC joins current backers OrbiMed Advisors, 5AM Ventures, New Leaf Venture Partners, Sprout Group, Delphi Ventures, and Mediphase Venture Partners in this funding round.…
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FDA Approves Diabetic Macular Edema Treatment
The U.S. Food and Drug Administration on Friday approved the drug ranibizumab, given by injection to treat diabetic macular edema, an eye disease that occurs in people with diabetes. Genentech, a division of the global pharmaceutical company Roche in South San Francisco, California, markets the drug under the name Lucentis. Diabetic macular edema can cause…
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Pfizer, Biotech to Partner on Autoimmune Disorders
The global pharmaceutical company Pfizer Inc. and biotechnology company Nodality Inc. in South San Francisco, California agreed to a partnership that provides Pfizer with access to Nodality’s cell signaling analysis technology to streamline development of treatments for autoimmune diseases, beginning with lupus. The financial amount of the multi-year year was not disclosed. Nodality has created…
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Trial Shows Generic Vaccine Helps Reverse Type 1 Diabetes
An early clinical trial indicates a generic vaccine that raises levels of an immune system modulator can kill autoimmune cells targeting the pancreas and temporarily restore insulin secretion in type 1 diabetes patients. Findings from the trial, conducted by researchers at Massachusetts General Hospital and Harvard Medical School in Boston, appear in the online journal…