Tag: preclinical
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Chip Device More Accurate for Drug Toxicity Than Animals
A plastic chip device lined with liver cells is shown to better predict drug toxicity in humans than lab animals, including drugs that progressed to failed clinical trials.
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Gene Therapy Combo Treats Multiple Age-Related Diseases
A bio-engineering team shows a single experimental gene therapy cocktail can reduce or reverse four age-related diseases in lab mice.
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Implanted Overdose Rescue Device Being Developed
An implanted device that senses an overdose of opioid drugs and dispenses an emergency rescue medicine is in development by two university labs.
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Nanoparticles Designed to Cross Blood-Brain Barrier
Nanoscale particles derived from viruses are shown in tests with lab mice to cross the blood-brain barrier, and reach nerve cells in the brain.
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Merck Gaining Gut Microbe Technology for Vaccines
Drug maker Merck & Co. is partnering with a developer of treatments for disease derived from microbes in the gut, for discovery of up to three vaccines.
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Dementia Drug Candidate in Preclinical Tests
A study is underway of a new treatment approach for dementia that targets inflammation and microscopic bleeding in the brain that can accompany Alzheimer’s disease.
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Nanotech Crispr Delivery in Development
Researchers in biochemistry and structural biology are designing a technique using nanoscale particles to safely deliver edited genes as a cancer treatment.
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Synthetic Biology Platform Designed for Vaccines
Researchers in France and the U.K. developed a modular technology with synthetic and computational biology for designing vaccines against infectious diseases.
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Stem Cells Grow New Spinal Disc Tissue
Tests with lab animals show stem cells derived from human donors can generate new spinal disc cells and tissue to help treat degenerating discs.
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Biotech Developing Genome-Adjusting Disease Treatments
A new biotechnology enterprise is creating disease treatments that address regions in the genome precisely regulating expression of proteins.