Tag: preclinical
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Esophagus Tissue from Stem Cells Grown, Implanted
Replacement engineered esophagus tissue grown from stem cells was shown in tests with pigs to be a feasible alternative to transplanting pieces from other parts of the body for people with esophagus cancer.
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Cancer Drug Seen to Reverse Autism Spectrum Symptoms
Small doses of a drug for blood-related cancers are shown in lab mice to reverse social symptoms often found in children with autism spectrum disorder, a condition characterized by limited social activity.
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Peptide Hydrogel Boosts Cancer Immunotherapies
A team at Rice University in Houston developed an injectable gel material that in lab mice slows the release of cancer immunotherapy drugs, enhancing the treatments’ effectiveness and reducing the need for repeated doses.
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3-D Biomaterial Boosts Personal Cancer Immunotherapy
A Harvard University bioengineering lab developed an injectable material designed to load up with proteins from a patient’s own tumors to induce immune reactions that fight that person’s cancer.
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Start-Up Developing Blood-Brain Barrier Treatments
A medical school professor in Singapore is starting a biotechnology company to discover and develop new drugs for neurological disorders based on his research with mechanisms for crossing the blood-brain barrier.
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Protein Engineered to Boost Nerve Cell Imaging
Engineers and neuroscientists developed a synthetic protein that illuminates electrical activity in animal brain nerve cells, with a process using robotics to test millions of protein candidates in cells.
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RNA Vaccine Shows Promise with Infant Viral Diseases
A vaccine using synthetic RNA, with protein instructions transcribed from one’s genetic code, is shown in tests with lab animals to protect against infections from cytomegalovirus, a virus affecting infants and transplant recipients.
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Gut Tissue From Stem Cells Simulated on Organ Chips
Researchers created working human gut tissue cells derived from stem cells, grown on plastic chips simulating intestinal diseases, as a tool for testing effectiveness and safety of treatments before given to patients.
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Open-Source Discovery Seeks Neglected Disease Drug
An international online collaboration is using an open process to discover new drug compounds to treat mycetoma, a slow-progressing inflammatory fungal disease occurring mainly in developing regions, which up to now is largely neglected.
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Biotech, Univ. Lab Partner on Stem Cells for Alzheimer’s
A biotechnology company specializing in stem cell therapeutics is licensing a process from Texas A&M University to produce exosomes — cellular delivery packages — from adult stem cells as possible therapies for Alzheimer’s disease.