Tag: preclinical
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Texas Vaccine Center Expanding R&D
A vaccine research center in Galveston, Texas is expanding its operations to add more basic and preclinical studies that lead to clinical trials resulting in more preventive and therapeutic vaccines.
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Overlooked Drugs Show Promise Against Superbugs
A class of antibiotics first discovered in the 1970s, but passed by as new drugs came on the market, are getting a second look as the need intensifies for better weapons to treat infections resistant to most antibiotics.
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Vaccine Shown Effective Against Range of Flu Viruses
An experimental vaccine made with protein-infused nanoscale particles was shown to provide long-lasting protection in lab mice against a broad range of common influenza viruses.
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NIH Funding Immune-Friendly Synthetic Vascular Grafts
A bioengineering lab is receiving a National Institutes of Health grant to advance development of more tolerable synthetic veins and arteries implanted in heart bypass patients.
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Small Business Grant Advances Drug Safety Test System
An award from National Institutes of Health is advancing a technology for testing the safety of drugs with heart muscle cells derived from stem cells before the drugs are tested on humans.
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Nerve Stimulation Shown to Reduce Diabetes Symptoms
Electric stimulation of a key nerve pathway was shown in lab animals to restore insulin sensitivity and glucose tolerance typically missing in people with type 2 diabetes.
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Stem Cell Patches Shown to Treat Heart Attack Damage
Human heart muscle patches made from stem cells helped fix damage and improve heart functions in tests with pigs induced with heart attacks.
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HIV Drugs Formulated Into Once-Weekly Capsules
Medical and engineering researchers developed and tested in pigs a technique for packing several drugs into a capsule taken once a week to prevent and treat HIV infections.
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Electronic Pulses, Sounds Shown to Reduce Tinnitus
A non-invasive system that combines coordinated electronic pulses and sounds is shown in tests with lab animals and humans to reduce tinnitus, phantom sounds often called ringing in the ears.
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Microneedle Patch Delivers Anti-Obesity Drugs
A skin patch containing hundreds of tiny porous needles is shown in lab mice to deliver drugs that turn ordinary body fat into calorie-burning brown fat to reduce body mass.