Tag: preclinical
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Radiation Enhances Nanoparticle Cancer Treatments
Targeting tumors with chemotherapy delivered in nanoparticles, preceded with radiation, was shown in lab mice to boost treatments in a range of cancers.
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3-D Printing Technique Devised for Replacement Cartilage
Biomedical engineers developed a process for directly printing replacement cartilage without the scaffolds needed in previous tissue engineering techniques.
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Grant for Research on Drugs to Improve Tissue Transplants
27 June 2016. Department of Defense is funding research on new drugs that aim to improve the quality of tissue and limbs for transplants donated from people whose brains stop working. DoD awarded the grant of nearly $1 million to the Institute for Transformative Molecular Medicine at Case Western Reserve University School of Medicine in…
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Start-Up Developing Nanomedicines for Transplants
A spin-off enterprise from Medical University of South Carolina is creating drug delivery techniques that make it safer for patients needing organ transplants.
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C. Difficile Infection Tested with Synthetic Gut Microbe
A biotechnology company reported on tests in mice of a synthetic treatment derived from gut microbes that prevents recurrence of C. difficile infections.
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Engineered Facial Bone Grown from Stem Cells
Engineers developed techniques for growing personalized replacement facial bone from stem cells that in tests with pigs precisely fit their recipients’ faces.
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St. Jude Hospital to Test Nanotech Flu Virus Drugs
31 May 2016. A company developing anti-viral drugs delivered in nanoscale particles is partnering with scientists at St. Jude Children’s Research Hospital to test drug candidates to treat influenza. Financial details of the agreement between NanoViricides Inc. in Shelton, Connecticut and St. Jude hospital in Memphis were not disclosed. NanoViricides makes drugs that fight dangerous…
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Boehringer, Inventiva Partner on Progressive Lung Disease
31 May 2016. Drug maker Boehringer Ingelheim and biopharmaceutical company Inventiva are collaborating on discovery of new treatments for idiopathic pulmonary fibrosis and related diseases causing fibrosis. The deal is expected to bring Inventiva, in Daix, France, as much as €170 million ($US 189 million), plus royalties on sales. Boehringer Ingelheim and Inventiva will jointly…
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Start-Up, Univ. Lab Partner on Computational Drug Discovery
25 May 2016. A two-year old company developing algorithms for drug discovery is collaborating with University of Chicago medical school to identify candidates to prevent atherosclerosis, or hardening of the arteries. Financial aspects of the agreement between twoXAR Inc. in Palo Alto, California and the lab of Yun Fang at University of Chicago were not…
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Zika Virus Cloned for Drug, Vaccine Development
17 May 2016. Researchers in Texas produced a genetically-engineered clone of the Zika virus to provide a testing platform for developers of diagnostics, vaccines, and treatments for the growing outbreak. The team from University of Texas Medical Branch in Galveston, led by geneticist Pei-Yong Shi, reported its findings yesterday in the journal Cell Host and Microbe.…