Tag: biomarkers
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Alliance Plans Adaptive Clinical Trials for Brain Cancer
12 November 2015. A global collaboration plans a series of clinical trials that address precise molecular targets testing treatments for glioblastoma multiforme, an aggressive brain cancer. The alliance combines medical teams, researchers, and patient advocates to employ adaptive clinical trials, a type of clinical study that enables investigators to adjust research tactics as results with…
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Computer Model Devised to Predict Drug Side Effects
2 November 2015. A systems biology lab developed a prototype computer model that can test for potential side effects of drugs from an individual’s blood sample. The team led by bioengineering professor Bernhard Palsson at University of California in San Diego published its proof-of-concept results last week in the journal Cell Systems. Palsson and first…
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Study Shows Blood Test Finds Early Pancreatic Cancer
12 October 2015. An evaluation of a blood test to find early stages of pancreatic cancer showed the test successfully identified early-stage cancer in the vast majority of study participants with the disease. The findings published by a team from diagnostics company VolitionRx in Belgium and Lund University in Sweden appeared last week in the…
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Partnership to Study Biomarkers in Liquid Biopsies
6 October 2015. DeNovo Sciences, a developer of liquid biopsies and analytics, is teaming with bioTheranostics, a cancer diagnostics company using molecular biomarkers, to test the feasibility of combining their technologies. Financial and intellectual property details of the collaboration were not disclosed. In testing for solid tumor cancers, such as lung or breast cancer, doctors…
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Immunotherapy Shown to Clear Some Cervical Lesions
17 September 2015. A clinical trial testing a vaccine designed to clear up cervical lesions or sores before they become cancerous, found women receiving the vaccine eradicated more of these lesions than those receiving a placebo. Results of the intermediate-stage trial, funded by Inovio Pharmaceuticals Inc. that makes the candidate vaccine, appear in today’s issue…
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Patent Awarded for Cancer-Detecting Blood Test
10 September 2015. VolitionRx, a developer of blood tests to screen for cancer, received a U.S. patent for its underlying technology that detects changes in basic cell proteins found in blood. Patent number 9,128,086 was issued by the U.S. Patent and Trademark Office on 8 September to four inventors and assigned to the company, incorporated…
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Foundation Supporting ALS Pilot Clinical Trials
1 July 2015. ALS Association is funding pilot studies with patients having amyotrophic lateral sclerosis to confirm biomarkers, or biochemical indicators, that improve responsiveness to therapies. The studies are being conducted by Neuraltus Pharmaceuticals Inc., a biopharmaceutical developer in Palo Alto, California, and University of Washington Medical Center in Seattle. ALS, also known as Lou…
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$50,000 Challenge Seeks Liver Disease Biomarkers
19 June 2015. A new challenge on InnoCentive asks for biomarkers indicating damage to the liver, conditions that today often require invasive procedures such as biopsies to diagnose. The competition has a total purse of $50,000 and a deadline for proposals of 17 August 2015. InnoCentive in Waltham, Massachusetts conducts open-innovation, crowdsourcing competitions for corporate…
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Drug Screening Target Designed for All Ebola Types
8 October 2014. Researchers at University of Utah and Navigen Inc., both in Salt Lake City, designed a synthetic peptide acting like a protein found in all strains of the Ebola virus that can serve as a target when screening for potential drugs to treat patients with the deadly disease. The team led by Utah…
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Early Clinical Trial to Test Leukemia Antibody Safety
17 September 2014. An early stage clinical trial at University of California in San Diego is testing the safety of an antibody that in lab animals decreases the number of chronic lymphocytic leukemia cells, the most common form of leukemia among adults. The study is led by UC-San Diego medical school professor Thomas Kipps, who…