Tag: preclinical
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Intrexon Spin-Off Developing Type 1 Diabetes Therapy
4 April 2016. A new subsidiary of the synthetic biology company Intrexon Corp. is creating a pill for people with type 1 diabetes to stop the disease’s damage in its early stages. The enterprise, known as Intrexon T1D Partners LLC, is a joint venture between Intrexon, in Germantown, Maryland, and White Rock Capital Partners a…
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Quick Tests for Mosquito-Borne Viruses Being Developed
22 March 2016. A Canadian company is developing diagnostic tests that it says can detect in 1 minute antibodies in blood indicating the early-stage presence of Zika and other mosquito-borne viruses. The company bioLytical Laboratories in Richmond, British Columbia says its proof-of-concept studies show the feasibility of these quick, point-of-care tests to diagnose dengue and…
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Implant Developed to Deliver Alzheimer’s Immunotherapy
18 March 2016. A neuroscience team from Ecole polytechnique fédérale de Lausanne, or EPFL, in Switzerland designed and implanted a capsule that in lab mice generates antibodies to reduce amyloid beta plaque accumulations in the brain associated with Alzheimer’s disease. Researchers from the lab of Patrick Aebischer, also EPFL’s president, published its findings in the…
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Allied-Bristol Licenses NYU Research, Starts New Company
17 March 2016. Allied-Bristol Life Sciences, a joint venture of Allied Minds and Bristol-Myers Squibb, is licensing research from New York University on signaling pathways affecting growth of tumors, for a new company begun under its tutelage. Financial aspects of the deal between Allied-Bristol and NYU were not disclosed. The new enterprise, known as iBeCa…
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Technique Speeds, Eases Bone Marrow Stem Cell Collection
16 March 2016. A lab in Australia developed a process that makes it easier and faster to harvest blood-forming stem cells for treating diseases such as leukemia. The team led by Susan Nilsson at Monash University in Clayton, Victoria published its findings in yesterday’s (15 March) issue of the journal Nature Communications. Transplants of hematopoietic…
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Roche Licensing Biotech Immunotherapies in $1B Deal
15 March 2016. The biotechnology company Blueprint Medicines, a developer of cancer treatments based on a patient’s precise genomic make-up, is partnering with the pharmaceutical company Roche on cancer immunotherapies. The agreement gives Roche options to license up to 5 small-molecule, or low molecular-weight therapies, in a deal that could bring Blueprint more than $1…
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Injected Drug Forms Anti-Cancer Nanoparticles in Tumors
15 March 2016. Medical researchers developed a drug delivery technique that in lab mice forms anti-cancer nanoparticles inside metastatic tumors, promising much more potent cancer treatments. The team led by Mauro Ferrari and Haifa Shen at Houston Methodist Research Institute in Texas published its findings in yesterday’s (14 March) issue of Nature Biotechnology; paid subscription…
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Beta Cell Patch Designed to Control Blood Glucose Levels
14 March 2016. A patch device made of beta cells — the cells that produce insulin — was shown to produce insulin on demand in lab mice induced with diabetes. A team from the biomedical engineering department jointly hosted by University of North Carolina in Chapel Hill and North Carolina State University in Raleigh published…
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Hydrogel Injection Tested to Treat Advanced Artery Disease
9 March 2016. A biomedical engineering team developed an injected hydrogel for advanced cases of peripheral artery disease that in lab animals improved blood flow and muscles in affected limbs. Researchers from University of California in San Diego, led by bioengineering professor Karen Christman, published their findings earlier this year in the Journal of the…
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Vaccine Developed to Stop Synthetic Opioids
17 February 2016. Fentanyl is a synthetic opioid drug for treating severe pain after surgery, and in some cases chronic pain, but is also highly addictive and increasingly abused, with growing numbers of overdose deaths. Researchers from Scripps Research Institute in La Jolla, California developed a vaccine that in lab mice prevents ingredients in fentanyl…