Tag: preclinical
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Preclinical Test Shows Vaccine Stops Cocaine Reaching Brain
Medical researchers at Weill Cornell Medical College in New York tested in primates a vaccine candidate against cocaine addiction, which showed the vaccine prevented cocaine from reaching the brain and inducing a dopamine high. The findings from the team led by genetic medical researcher Ronald Crystal, with colleagues from Weill Cornell, Columbia University, and Scripps…
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Surgical Agents Developed for Biopsies in Confined Spaces
Researchers at Johns Hopkins University in Baltimore created and tested microscopic devices powered by body heat that collect tissue samples from patients for biopsies. A team led by Johns Hopkins physician Florin Selaru and engineer David Gracias published its findings in the April issue of the journal Gastroenterology, as well as the 25 January issue…
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FDA OKs Trial of Biopolymer to Treat Spinal Cord Injury
InVivo Therapeutics, a medical device developer in Cambridge, Massachusetts, says it received approval from the U.S. Food and Drug Administration to begin a clinical trial to test the company’s bio-based polymer scaffolding as a treatment for acute traumatic spinal cord injury. The agency’s approval came in the form of an Investigational Device Exemption that allows…
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Lab-On-Chip Maker Lands $9.2M in Early Round Venture Funds
Hurel Corporation, a developer of preclinical testing devices in New Brunswick, New Jersey, raised $9.2 million in its first round of venture fund raising after initial start-up. The round was organized by Spring Mountain Capital, a private equity investment management company in New York. No other participants in the round were disclosed. Hurel Corp. designs…
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Harvard Institute, Sony to Partner on Organs-on-Chips
The Wyss Institute for Biologically Inspired Engineering at Harvard University in Massachusetts and Sony Corporation’s optical media division (Sony DADC) will collaborate on developing plastic chips that emulate human organs. Financial terms and timetable of the deal were not disclosed. Chips that emulate human organs are made of clear, flexible polymer plastic, about the size…
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Personalized Chemotherapy Devised from Patients’ Tumors
Researchers at Johns Hopkins University in Baltimore developed a new lab technique to personalize the selection of chemotherapy drugs, with cell lines based on patients’ own tumors and genetically engineered mice. The findings of the team led by Johns Hopkins professor James Eshleman appear online in a recent issue of the journal Clinical Cancer Research…
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Asthma Drug Reveals Potential as Diabetes, Obesity Treatment
A drug long prescribed for asthma and canker sores has been shown in tests on mice to reverse obesity and diabetes. Researchers from University of Michigan in Ann Arbor, and labs in California and Australia, published their findings yesterday online in the journal Nature Medicine (paid subscription required). Alan Saltiel, director of Michigan’s Life Sciences…
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Nanotech Capsule Delivers Cancer Drugs, Spares Healthy Cells
Engineers at University of California in Los Angeles and University of Southern California developed tiny degradable capsules that can deliver cancer treatments directly to tumors, sparing healthy cells from damage. The team led by UCLA professor Yi Tang published its findings online in the journal Nano Today (paid subscription required). Tang (pictured left) and colleagues…
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Janssen R&D Opens Lab Space to Individual Entrepreneurs
Janssen Labs at San Diego, part of Janssen Research and Development and the pharmaceutical company Johnson & Johnson, is expanding its open laboratory facilities to individual life science entrepreneurs to conduct early stage research. The facility, open for a year, is already home to 18 start-up companies in the life sciences. Janssen Labs is housed…
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Company, University to Develop 3D Models for Cancer Research
Organovo Holdings Inc. in San Diego, with Oregon Health and Science University in Portland, will develop three dimensional human tissue models to replicate cancer disease for lab testing of potential therapies. The partnership, for which financial terms were not disclosed, will apply Organovo’s 3D printing technology that builds tissue models for testing cancer treatments more…