Tag: preclinical
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Mayo Clinic, Korean Biotech to Collaborate on ALS Research
Mayo Clinic’s campus in Jacksonville, Florida and SK Biopharmaceuticals in Seoul, South Korea have agreed to develop new treatments for amyotrophic lateral sclerosis (ALS), better known as Lou Gehrig’s disease. The collaboration will center around the work of Mayo Clinic’s Leonard Petrucelli, who heads the neuroscience research department at the Jacksonville campus. ALS results in…
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Biotech Developing Anti-Cancer Drugs Gets $15M Investment
Tensha Therapeutics in Cambridge, Massachusetts says it has received $15 million in early stage financing to advance treatments for cancer by regulating the transcription of disease-associated genes. The series A investment — the first round of funding after a company’s initial seed capital — is provided by HealthCare Ventures, life science venture capital firm, also…
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Biotech, NGO Partnership Advances Sleeping Sickness Drug
A consortium of two biotechnology companies and non-government organization have completed preclinical studies of a potential treatment for sleeping sickness. The partners — Anacor Pharmaceuticals in Palo Alto, California, SCYNEXIS Inc. in Research Triangle Park, North Carolina, and Drugs for Neglected Diseases initiative (DNDi) in Geneva, Switzerland — published their findings in the journal PLoS…
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Genentech Gets Rights, Can Buy Out Biotech Research Program
The biotechnology company Forma Therapeutics in Cambridge, Massachusetts says it has an agreement with Genentech, a member of the Roche Group, granting Genentech exclusive rights to acquire one of Forma’s pre-clinical small molecule cancer research programs. The specific cancer target of the therapy under development is not disclosed. The agreement begins as a research collaboration…
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New Process Integrates Cancer Lab Studies, Clinical Trials
A joint project of National Cancer Institute (NCI), Jackson Laboratory in Bar Harbor, Maine, and University of California at Davis plans to develop a more consistent model for integrating the results of preclinical cancer research with human clinical trials. The new process comes under NCI’s Advanced Technology Partnerships Initiative and its Center for Advanced Preclinical…
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Company Tests Stem Cells Creating Liver Cells in Animals
International Stem Cell Corporation (ISCO) in Carlsbad, California says it completed the first animal lab tests of hepatocytes — cells that make up most of the tissue in the liver — derived in the lab from human unfertilized egg stem cells. The results of the tests will be presented at scientific meetings in May and…
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H1N1 Drug Gets Positive Results in Preclinical Tests
AVI BioPharma Inc. of Bothell, Washington reported positive results from two preclinical studies evaluating the therapeutic potential of its drug AVI-7100 against a fully virulent pandemic H1N1 virus, also known as swine flu. The results showed statistically significant reductions in average viral titer — a quantitative measure of biological activity in a recombinant virus —…