{"id":104,"date":"2010-07-14T10:03:45","date_gmt":"2010-07-14T14:03:45","guid":{"rendered":"http:\/\/sciencebusiness.technewslit.com\/?p=104"},"modified":"2010-07-14T10:03:45","modified_gmt":"2010-07-14T14:03:45","slug":"genomic-behavior-profile-developed-of-human-arteries","status":"publish","type":"post","link":"https:\/\/technewslit.com\/sciencebusiness\/?p=104","title":{"rendered":"Genomic Behavior Profile Developed of Human Arteries"},"content":{"rendered":"<p><a href=\"http:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/07\/HumanHeartArteries_YaleMedicineWMC_200x250.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-105\" title=\"HumanHeartArteries_YaleMedicineWMC_200x250\" src=\"http:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/07\/HumanHeartArteries_YaleMedicineWMC_200x250.png\" alt=\"Human heart and arteries (Yale School of Medicine\/Wikimedia Commons)\" width=\"200\" height=\"249\" srcset=\"https:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/07\/HumanHeartArteries_YaleMedicineWMC_200x250.png 200w, https:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/07\/HumanHeartArteries_YaleMedicineWMC_200x250-120x150.png 120w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a>Scientists at <a href=\"http:\/\/www.hemoshear.com\/home\">HemoShear LLC<\/a> in Charlottesville, Virginia, have produced a profile of all genes that influence the biology and function of the human artery system. The research offers insights into the range of genes found in specific cell-types that make up human arteries.<\/p>\n<p>Brett Blackman, one of the company&#8217;s founders, said HemoShear&#8217;s team &#8220;identified individual genes and novel gene networks that may play an important role in inflammation and atherosclerosis, which remain the leading causes of death in the western world.&#8221; Atherosclerosis is a blood vessel inflammatory disease characterized by build-up of plaque in the arteries, which limits blood flow and can lead to heart attack and stroke. Blackman added, &#8220;[A]s we uncover and validate new gene targets, we plan to collaborate with pharmaceutical companies to develop improved treatments for vascular disease.&#8221;<\/p>\n<p>HemoShear is a developer of cell-based, human surrogate models for discovery and assessment of new drug compounds. According to <a href=\"http:\/\/www.hemoshear.com\/article\/19\">the company&#8217;s announcement<\/a>, its scientists conducted experiments with newly harvested human cells to replicate healthy regions of the artery system as well regions susceptible to disease. The experiments aimed to develop a baseline understanding of human artery biology and to gain insight into how arterial inflammation and early atherosclerosis develop in humans.<\/p>\n<p>Image: Yale University School of Medicine\/<a href=\"http:\/\/commons.wikimedia.org\/wiki\/File:Human_heart_with_coronary_arteries_new.png\">Wikimedia Commons<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists at HemoShear LLC in Charlottesville, Virginia, have produced a profile of all genes that influence the biology and function of the human artery system. The research offers insights into the range of genes found in specific cell-types that make up human arteries. Brett Blackman, one of the company&#8217;s founders, said HemoShear&#8217;s team &#8220;identified individual [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[31],"class_list":["post-104","post","type-post","status-publish","format-standard","hentry","category-products","tag-biomedical"],"_links":{"self":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/104","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=104"}],"version-history":[{"count":2,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/104\/revisions"}],"predecessor-version":[{"id":107,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/104\/revisions\/107"}],"wp:attachment":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=104"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=104"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=104"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}