{"id":5779,"date":"2011-08-25T15:56:36","date_gmt":"2011-08-25T19:56:36","guid":{"rendered":"http:\/\/sciencebusiness.technewslit.com\/?p=5779"},"modified":"2011-08-25T15:56:36","modified_gmt":"2011-08-25T19:56:36","slug":"small-business-grant-awarded-for-blood-vessel-drug-database","status":"publish","type":"post","link":"https:\/\/technewslit.com\/sciencebusiness\/?p=5779","title":{"rendered":"Small Business Grant Awarded for Blood Vessel Drug Database"},"content":{"rendered":"<figure id=\"attachment_472\" aria-describedby=\"caption-attachment-472\" style=\"width: 200px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/08\/DNAFragment_WMC_200.png\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-472\" title=\"DNAFragment_WMC_200\" src=\"http:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/08\/DNAFragment_WMC_200.png\" alt=\"DNA fragment (Wikimedia Commons)\" width=\"200\" height=\"221\" srcset=\"https:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/08\/DNAFragment_WMC_200.png 200w, https:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/08\/DNAFragment_WMC_200-135x150.png 135w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><figcaption id=\"caption-attachment-472\" class=\"wp-caption-text\">(Wikimedia Commons)<\/figcaption><\/figure>\n<p><a href=\"http:\/\/www.hemoshear.com\/article\/27\">HemoShear LLC<\/a>, a biotechnology company in Charlottesville, Virginia has been awarded a Phase 2 Small Business Innovation Research (SBIR) grant award from National Institutes of Health (NIH). The grant of up to $4.3 million will fund profiles of the effects of 50 known drugs on the human blood vessel system.<\/p>\n<p>The database will help predict the safety and effectiveness of potential new drug candidates. HemoShear will use its <a href=\"http:\/\/www.hemoshear.com\/our-technology\">bioinformatics technology<\/a> to develop a predictive gene signature to score new drug compounds for vascular safety risk. The company says there are no technologies available to the pharmaceutical industry to address this need.<\/p>\n<p>This grant is the third <a href=\"http:\/\/www.hemoshear.com\/research-grants\">SBIR award<\/a> HemoShear has received from NIH in two years. The company received a Phase 1 SBIR grant in April 2010 which funded development of what it calls a human surrogate vascular inflammation system. This system has been validated and is being used in customer research programs. HemoShear was awarded a second Phase 1 SBIR grant in April 2011 to develop a rodent liver surrogate system as a first step towards development of an advanced human liver system.<\/p>\n<p>Phase 1 <a href=\"http:\/\/www.sbir.gov\/about\/about-sbir\">SBIR grants<\/a> establish the technical merit, feasibility, and commercial potential of proposed research or R&amp;D projects, and determine the quality of performance of the small business awardee organization before providing further federal support. Phase 2 grants support the continuation of the R&amp;D, with funding levels determined by the scientific and technical merit and commercial potential of the project.<\/p>\n<p>Only small, for-profit businesses &#8212; no more than 500 employees &#8212; with 51 percent or greater ownership by American citizens or resident aliens can qualify for SBIR grants.<\/p>\n<p>Read more: <a href=\"http:\/\/sciencebusiness.technewslit.com\/?p=104\">Genomic Behavior Profile Developed of Human Arteries<\/a><\/p>\n<p style=\"text-align: center;\">*\u00a0\u00a0\u00a0\u00a0 *\u00a0\u00a0\u00a0\u00a0 *<\/p>\n","protected":false},"excerpt":{"rendered":"<p>HemoShear LLC, a biotechnology company in Charlottesville, Virginia has been awarded a Phase 2 Small Business Innovation Research (SBIR) grant award from National Institutes of Health (NIH). The grant of up to $4.3 million will fund profiles of the effects of 50 known drugs on the human blood vessel system. The database will help predict [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[31,21,109,38,64,39],"class_list":["post-5779","post","type-post","status-publish","format-standard","hentry","category-finance","tag-biomedical","tag-biotech","tag-computer-science","tag-grant","tag-life-sciences","tag-nih"],"_links":{"self":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/5779","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5779"}],"version-history":[{"count":3,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/5779\/revisions"}],"predecessor-version":[{"id":5782,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/5779\/revisions\/5782"}],"wp:attachment":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5779"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5779"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5779"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}