{"id":6758,"date":"2011-11-01T17:00:42","date_gmt":"2011-11-01T21:00:42","guid":{"rendered":"http:\/\/sciencebusiness.technewslit.com\/?p=6758"},"modified":"2011-11-01T17:00:42","modified_gmt":"2011-11-01T21:00:42","slug":"nih-to-fund-diabetescardiovascular-biomarker-collaboration","status":"publish","type":"post","link":"https:\/\/technewslit.com\/sciencebusiness\/?p=6758","title":{"rendered":"NIH to Fund Diabetes\/Cardiovascular Biomarker Collaboration"},"content":{"rendered":"
\"Chad<\/a>
Biodesign Institute researcher Chad Borges loads a sample into a mass spectrometer. (Arizona State University)<\/figcaption><\/figure>\n

Researchers at Arizona State University<\/a> in Tempe will lead a team funded by National Institutes of Health to discover proteins or biomarkers that help predict cardiovascular disease and to assess new treatments for people with type 2 diabetes. The $5 million, four-year project will include scientists from the Phoenix VA Health Care System, Pfizer Inc., and University of Arizona.<\/p>\n

The team is led by chemistry professor Randy Nelson<\/a>, director of the Molecular Biosignatures Analysis Unit at ASU’s Biodesign Institute. Nelson says the team’s goal is to “discover, validate and translate novel protein biomarkers for cardiovascular complications in type 2 diabetes and their use in drug development.” The need for the project, notes Nelson, arises from the lack of standard biomarkers to identify people with type 2 diabetes who are more likely to develop cardiovascular disease.<\/p>\n

The study is expected to examine and validate biomarkers in people with diabetes, some of whom will have had a heart attack. No single biomarker will probably have enough predictive power to assess heart attack risk. Panels of biomarkers will more likely be needed to identify drug targets.<\/p>\n

Team member Peter Reaven, will oversee the selection of target biomarkers and clinical work, including patient recruitment at the Phoenix VA Health Care System. Pfizer is expected to play a key role in translating prognostic biomarkers of cardiovascular disease risk for decision-making during drug development for type 2 diabetes. Others team members include Chad Borges at ASU’s Biodesign Institute (pictured at top); Juraj Koska of the Phoenix VA Health Care System; and Serrine Lau, Craig Stump, and Yassine Hussein at the University of Arizona’s BIO5 Institute.<\/p>\n

“One advantage to our team approach,” says Reaven, “is that it will integrate, from the very beginning, the many aspects and disciplines required for a pipeline of biomarker discovery, validation, and translation.”<\/p>\n

Read more: Biomarker Test Can Reduce Heart Failure Complications<\/a><\/p>\n

*\u00a0\u00a0\u00a0\u00a0 *\u00a0\u00a0\u00a0\u00a0 *<\/p>\n","protected":false},"excerpt":{"rendered":"

Researchers at Arizona State University in Tempe will lead a team funded by National Institutes of Health to discover proteins or biomarkers that help predict cardiovascular disease and to assess new treatments for people with type 2 diabetes. The $5 million, four-year project will include scientists from the Phoenix VA Health Care System, Pfizer Inc., […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,16],"tags":[50,31,28,38,64,39,27,26],"class_list":["post-6758","post","type-post","status-publish","format-standard","hentry","category-finance","category-ventures","tag-biomarkers","tag-biomedical","tag-clinical-trials","tag-grant","tag-life-sciences","tag-nih","tag-pharmaceuticals","tag-university"],"_links":{"self":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/6758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6758"}],"version-history":[{"count":5,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/6758\/revisions"}],"predecessor-version":[{"id":6764,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/6758\/revisions\/6764"}],"wp:attachment":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}