{"id":8996,"date":"2012-04-11T12:08:42","date_gmt":"2012-04-11T16:08:42","guid":{"rendered":"http:\/\/sciencebusiness.technewslit.com\/?p=8996"},"modified":"2012-04-11T12:08:42","modified_gmt":"2012-04-11T16:08:42","slug":"biotech-licenses-brain-nervous-system-treatment-technology","status":"publish","type":"post","link":"https:\/\/technewslit.com\/sciencebusiness\/?p=8996","title":{"rendered":"Biotech Licenses Brain-Nervous System Treatment Technology"},"content":{"rendered":"<figure id=\"attachment_1420\" aria-describedby=\"caption-attachment-1420\" style=\"width: 250px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/10\/BrainScan_NIMH.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1420\" title=\"BrainScan_NIMH\" src=\"http:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/10\/BrainScan_NIMH.jpg\" alt=\"Brain scan (National Institute of Mental Health)\" width=\"250\" height=\"250\" srcset=\"https:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/10\/BrainScan_NIMH.jpg 250w, https:\/\/technewslit.com\/sciencebusiness\/wp-content\/uploads\/2010\/10\/BrainScan_NIMH-150x150.jpg 150w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/><\/a><figcaption id=\"caption-attachment-1420\" class=\"wp-caption-text\">(National Institute of Mental Health)<\/figcaption><\/figure>\n<p><a href=\"http:\/\/www.aabgu.org\/media-center\/news-releases\/bgu-drug-delivery-platform-central-nervous-system-diseases.html\">Ben-Gurion University of the Negev<\/a> in Israel says it has licensed a technology from its labs that crosses the blood-brain barrier to deliver drugs for treating disorders of the brain and central nervous system. The V-Smart technology, as its called, was licensed exclusively to <a href=\"http:\/\/www.laurensciences.com\/\">Lauren Sciences LLC<\/a>, a privately held biotechnology company in New York.<\/p>\n<p>Lauren Sciences is expected to develop the technology as a platform for treating a variety of diseases that affect the central nervous system, such as Parkinson&#8217;s, Alzheimer&#8217;s, Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig&#8217;s Disease), and brain tumors.<\/p>\n<p>The <a href=\"http:\/\/cmsprod.bgu.ac.il\/NR\/rdonlyres\/DB3505F1-2D48-4E71-B43A-120952269433\/83916\/CrossingtheBBBwithTargetedNanoVesiclesv02.pdf\">V-Smart technology<\/a> uses tiny &#8212; 20 to 100 nanometers; 1 nanometer equals 1 billionth of a meter &#8212; lipid bubbles called vesicles that can cross the blood-brain barrier to deliver drugs to specific targets in the brain. The nano-vesicles act as building blocks for the delivery of drugs in the desired quantities.<\/p>\n<p>The technology was developed by Ben-Gurion researchers Sabrina Grinberg, Charles Linder, and Eliahu Heldman, who also serves as the chief technology officer of Lauren Sciences. Heldman says their preclinical studies show the nano-scale vesicles, &#8220;encapsulate small molecules, peptides, proteins and nucleic acids, cross the [blood-brain barrier] and release their encapsulated contents in the brain.&#8221; The researchers say there is an unmet need for a safe, effective, and reliable transport system to deliver chemotherapeutic agents to the brain of patients with brain cancer and other central nervous system disorders.<\/p>\n<p>Lauren Sciences was recently awarded a grant from the <a href=\"http:\/\/www.michaeljfox.org\/research_MJFFfundingPortfolio_searchableAwardedGrants_3.cfm?ID=948\">Michael J. Fox Foundation<\/a> to develop a V-Smart treatment for Parkinson&#8217;s disease. The university says the V-Smart technology is protected by several worldwide patents filed by BGN Technologies Ltd., its technology transfer office.<\/p>\n<p>Read more: <a href=\"http:\/\/sciencebusiness.technewslit.com\/?p=3655\">Organic Nanoparticle in Development for Cancer Drug Delivery<\/a><\/p>\n<p style=\"text-align: center;\">*\u00a0\u00a0\u00a0\u00a0 *\u00a0\u00a0\u00a0\u00a0 *<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ben-Gurion University of the Negev in Israel says it has licensed a technology from its labs that crosses the blood-brain barrier to deliver drugs for treating disorders of the brain and central nervous system. The V-Smart technology, as its called, was licensed exclusively to Lauren Sciences LLC, a privately held biotechnology company in New York. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[31,21,51,96,86,74,114,84,64,77,18,29,27,26],"class_list":["post-8996","post","type-post","status-publish","format-standard","hentry","category-i-p","tag-biomedical","tag-biotech","tag-cancer","tag-chemistry","tag-engineering","tag-entrepreneurs","tag-israel","tag-licensing","tag-life-sciences","tag-medical-device","tag-nanotechnology","tag-patent","tag-pharmaceuticals","tag-university"],"_links":{"self":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/8996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8996"}],"version-history":[{"count":3,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/8996\/revisions"}],"predecessor-version":[{"id":8999,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=\/wp\/v2\/posts\/8996\/revisions\/8999"}],"wp:attachment":[{"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8996"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8996"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/technewslit.com\/sciencebusiness\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}