Tag: pharmaceuticals
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Many Large Clinical Trials Remain Unpublished
Medical researchers at University of North Carolina in Chapel Hill found some three in 10 clinical trials having 500 or more participants remain unpublished, with results from the vast majority of unpublished studies not made available on ClinicalTrials.gov, the U.S. government’s database. Findings from the team led by emergency medicine professor Timothy Platts-Mills were reported…
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Contract Awarded for Influenza Vaccine and Immune Booster
NanoBio Corporation in Ann Arbor, Michigan received a new contract from National Institute of Allergy and Infectious Diseases, part of National Institutes of Health, for development of a pandemic influenza vaccine and adjuvant to boost the immune response of that vaccine. The initial contract value is $5.5 million, but the company says it would be…
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Trial Underway Testing Genetic Disease Stem Cell Therapy
A clinical trial is underway testing a therapy based on a patient’s own stem cells to treat childhood cerebral adrenoleukodystrophy (CCALD), a rare genetic disease affecting mainly boys. The trial began treating the first of an expected 15 patients testing the therapy made by bluebird bio, a biotechnology company in Cambridge, Massachusetts and Paris, France.…
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Clinical Trial Tests Ultrasound Device to Boost Stroke Drugs
A clinical trial found an ultrasound device safe for ischemic stroke patients and helpful for many of these patients in dissolving blood clots in their brains. Researchers from University of Texas Health Science Center in Houston, with colleagues from University of Alabama-Birmingham and medical centers in Germany, tested the device in an intermediate-stage trial with 20…
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Panel Recommends Steps for Sharing Patient Trial Data
A study group of academics and pharmaceutical industry experts recommends expanding access to data from clinical trials, including data on individual participants, under tight protocols and conditions.
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Consortium Formed for Antibiotic Resistance Drug Discovery
A collaboration of Anacor Pharmaceuticals in Palo Alto, California with Colorado State University and University of California in Berkeley is researching new types of antibiotics to treat a broad range of infections, including those resistant to current antibiotics. The $13.5 million, 3.5 year project is funded by the Defense Threat Reduction Agency, part of the…
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Challenge Seeks Better Insecticide Performance Test Methods
A new challenge on InnoCentive is looking for new methods or processes for tracking the interactions between insecticides and the pests they aim to kill. The competition has a total purse of $10,000 and a deadline of 18 November 2013 for proposals (free registration required). InnoCentive in Waltham, Massachusetts conducts open-innovation, crowd-sourcing competitions for corporate…
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Heat, Iron-Oxide Nanoparticles Improve Cancer Drug Delivery
Pharmaceutical and engineering researchers at Oregon State University in Corvallis developed a technique with heated iron-oxide nanoparticles that in lab tests was shown to kill ovarian cancer cells with chemotherapy drugs. The team led by Oregon State pharmacy professor Oleh Taratula published its findings this month in an advance online paper in the International Journal of…
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Super-Antioxidant Developed from Catalyst Nanoparticles
Chemists and bioengineers at Rice University in Houston developed an antioxidant from an element used in catalytic converters that they found to be many times more powerful than antioxidants now on the market. The team from the labs of Vicki Colvin and Laura Segatori published their findings earlier this month in the journal ACS Nano…
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Genetic-Based Antibiotic Found Effective in Lab Tests
Researchers at Oregon State University, University of Texas Southwestern Medical Center, and the biotechnology company Sarepta Therapeutics tested in lab mice an antibiotic developed from synthetic genetic material that kills bacteria resistant to traditional antibiotics. Their findings appear online today in the Journal of Infectious Diseases (paid subscription required). The team from the labs of…